VenaSeal for Varicose Veins

Close varicose veins with medical adhesive technology—no tumescent anesthesia, no thermal energy, just proven results with minimal discomfort and immediate return to activities.
VenaSeal for Varicose Veins
Understanding VenaSeal

What Is VenaSeal?

 VenaSeal™ is an FDA-approved, minimally invasive procedure that uses a medical adhesive to close varicose veins caused by chronic venous insufficiency. Under ultrasound guidance, a small catheter delivers a specially formulated cyanoacrylate adhesive directly into the diseased vein. The adhesive immediately seals the vein walls together, permanently closing the problematic vessel. Blood flow instantly reroutes through healthier veins, eliminating symptoms and improving appearance.

Unlike thermal-based treatments, VenaSeal requires no tumescent anesthesia—the multiple injections used to numb and protect surrounding tissue. This unique characteristic makes VenaSeal notably comfortable, with most patients reporting minimal sensation during treatment. The procedure takes approximately 30-45 minutes, and patients typically resume normal activities immediately with minimal to no restrictions.

Key Benefits:

  • No Tumescent Anesthesia:
    Single access point, minimal injections, greater comfort.
  • Non-Thermal Technology:
    No heat energy, eliminating thermal injury risk.
  • Immediate Activity:
    Resume normal activities immediately after treatment.
  • Single Injection:
    One small access point versus multiple anesthesia injections.
  • Minimal Restrictions:
    No compression stockings required in most cases.

What Conditions Does VenaSeal Treat?

VenaSeal is specifically designed to treat symptomatic varicose veins resulting from superficial venous reflux—when faulty valves allow blood to flow backward and pool in leg veins.

  • Varicose Veins: VenaSeal targets incompetent saphenous veins (great or small saphenous) feeding visible, bulging varicose veins. By sealing the source vein with medical adhesive, surface varicosities diminish and symptoms resolve.
  • Chronic Venous Insufficiency (CVI): When vein valves malfunction, blood accumulates in lower legs causing swelling, aching, and skin changes. VenaSeal restores proper circulation by permanently closing the diseased pathway.
  • Leg Pain and Heaviness: Persistent aching, throbbing, or fatigue in legs—particularly after standing—often stems from venous reflux. Sealing the damaged vein with VenaSeal typically relieves discomfort within days to weeks.
  • Leg Swelling and Edema: Chronic ankle and calf swelling caused by poor venous return improves as healthy veins resume normal drainage following VenaSeal closure.
  • Restless Leg Syndrome (RLS): When RLS symptoms originate from underlying venous insufficiency, VenaSeal treatment can significantly reduce nighttime leg discomfort and restlessness.
The Science Behind VenaSeal

The VenaSeal™ Process

While the following steps outline the standard VenaSeal procedure, Dr. Verebelyi customizes every treatment to your unique venous anatomy, symptom profile, and lifestyle requirements.

VenaSeal for Varicose Veins
  1. Ultrasound Mapping: Using advanced ultrasound, Dr. Verebelyi precisely maps your venous system, identifying diseased veins and optimal access points. This diagnostic imaging ensures accurate catheter placement and complete treatment coverage.
  2. Single Access Point: A small needle creates one tiny access point—typically near the knee or below. This single entry eliminates the multiple injections required with thermal procedures, significantly improving patient comfort.
  3. Catheter Advancement: Under continuous ultrasound guidance, a specialized catheter advances through the diseased vein to the treatment starting point. Real-time imaging ensures precise positioning throughout.
  4. Adhesive Delivery: Medical-grade cyanoacrylate adhesive is delivered in small amounts along the vein length as the catheter withdraws. The adhesive immediately bonds vein walls together, creating permanent closure.
  5. Vein Compression: Brief external pressure is applied at each adhesive delivery point to ensure complete vein wall contact and optimal seal formation.
  6. Immediate Circulation Rerouting: Once closed, blood instantly redirects through healthy, functional veins designed to handle increased flow. The body gradually absorbs the sealed vein over subsequent months.
The Treatment Process

What to Expect

Our comprehensive approach begins with thorough evaluation and continues through every stage of your treatment journey, ensuring optimal results and complete patient comfort.
before laser hair removal

Before Treatment

Your consultation includes comprehensive vascular ultrasound performed by Dr. Verebelyi, a Registered Vascular Technician (RVT) with over 20 years of diagnostic expertise. You’ll receive personalized treatment planning and pre-procedure guidance.

  • Diagnostic Ultrasound: Complete venous mapping confirms candidacy
  • Treatment Planning: Customized approach based on your anatomy
  • Pre-Procedure Instructions: Medication guidance, clothing recommendations
  • Consultation Duration: 30-45 minutes

During Treatment

A single access point is created with minimal discomfort. You’ll feel slight pressure as the catheter advances, but VenaSeal’s non-thermal approach eliminates the multiple injections required with other procedures.

  • Single Access: One small needle stick, minimal injection
  • No Tumescent Anesthesia: Eliminates multiple numbing injections
  • Ultrasound Guided: Continuous visualization ensures precision
  • Minimal Sensation: Pressure and slight tugging, typically no pain
  • Treatment Duration: 30-45 minutes per vein

After Treatment

No compression stockings are typically required. Walk for 10-15 minutes in-office before leaving. Most patients drive themselves home and resume normal activities immediately with minimal to no restrictions.

  • Immediate Walking: 10-15 minutes in-office before departure
  • Minimal Side Effects: Possible tenderness, minor bruising
  • No Compression Required: Most patients need no compression garments
  • Activity Freedom: Resume normal activities immediately
  • Return to Exercise: Light activity same day, full activity within days

VenaSeal™ Results & Recovery

While VenaSeal delivers consistently strong outcomes, individual results depend on venous anatomy, symptom severity, and adherence to post-treatment guidance. The following timelines represent typical experiences based on clinical data and our practice outcomes.

Immediate & Short-Term Recovery

  • Same-Day Activity: Resume normal activities immediately
  • Driving Permitted: Most patients drive themselves home
  • Return to Work: Same day or next day for most occupations
  • Exercise Freedom: Light activity immediately, full activity within days
  • No Compression Required: Most patients need no compression garments
  • Common Side Effects: Minimal bruising, mild tenderness at access site (1-2 weeks)
  • Visible Improvement: Begins within 2-4 weeks as vein is absorbed

Long-Term Outcomes

  • Success Rate: 92-96% complete vein closure at 3 years
  • Symptom Resolution: Pain, heaviness, swelling improve within 4-6 weeks
  • Vein Absorption: Treated vein gradually absorbed over 3-6 months
  • Aesthetic Results: Smoother, clearer skin with reduced visible veins
  • Quality of Life: Improved mobility, reduced discomfort, enhanced confidence
  • Durability: Closed veins remain sealed; new veins may develop over time
  • Follow-Up: Post-treatment ultrasound typically at 1 week and 3 months
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Questions About VenaSeal™? Ask Ava.

Ava, our AI assistant, is available 24/7 to provide instant, personalized responses to your questions about VenaSeal—including candidacy, procedure details, recovery expectations, insurance coverage, and how VenaSeal compares to other varicose vein treatments.
Our Team

20+ Years of Vascular Excellence

Laser Vein Treatments

The team at Colorado Skin & Vein, led by David Verebelyi, MD, RVT, and Christina Jordan, FNP, CANS, has been treating vein conditions for over two decades, earning a reputation as leaders in advanced vascular and laser medicine.

Dr. David Verebelyi serves as Chief of Laser Surgery at Colorado Skin & Vein, bringing over 20 years of specialized experience in venous care and minimally invasive vein treatments.

Common Questions

VenaSeal™ Frequently Asked Questions

How is VenaSeal different from other varicose vein treatments?

 VenaSeal uses medical adhesive rather than heat energy to close veins. This eliminates the need for tumescent anesthesia—multiple numbing injections required with thermal procedures. Most patients experience significantly less discomfort and require no compression stockings.

Most patients report minimal discomfort. You’ll feel one needle stick for access and slight pressure as the catheter advances. Without tumescent anesthesia injections, VenaSeal is notably more comfortable than thermal ablation procedures.

The procedure typically takes 30-45 minutes per vein treated. Including preparation and post-procedure instructions, plan for approximately 60-75 minutes in-office.

Most patients require no compression stockings following VenaSeal treatment. Some physicians recommend brief compression for comfort, but extended compression is typically unnecessary due to the non-thermal nature of the procedure.

Most patients return to work immediately or the next day. The lack of tumescent anesthesia and minimal discomfort allows rapid return to all activities including desk work, standing occupations, and physical labor.

Light activity is permitted immediately. Most patients resume full exercise routines within 2-3 days. Unlike thermal procedures, VenaSeal causes minimal inflammation, allowing faster activity resumption.

VenaSeal is typically covered when medically necessary for symptomatic varicose veins caused by venous reflux. Coverage requires documented symptoms and diagnostic ultrasound confirming venous insufficiency. We verify benefits and obtain authorization before treatment.

Clinical studies demonstrate 92-96% complete vein closure rates at 3 years post-treatment. VenaSeal shows comparable long-term effectiveness to thermal ablation with enhanced patient comfort.

The adhesive permanently bonds the vein walls closed. The sealed vein remains in your body but becomes fibrous tissue gradually absorbed over 3-6 months. It no longer carries blood and eventually becomes undetectable.

The specific vein treated with VenaSeal remains permanently closed. However, genetic predisposition may cause new varicose veins to develop in other locations over time. New veins can be treated if they become symptomatic.

Common side effects include mild bruising and tenderness at the access site, resolving within 1-2 weeks.

Symptom relief (reduced pain, heaviness, swelling) typically begins within days to weeks. Visible improvement in vein appearance becomes noticeable at 3-4 weeks and continues improving over 3-6 months as the vein is absorbed.

VenaSeal effectively treats great and small saphenous vein reflux—the root cause of most varicose veins. Very tortuous veins or specific anatomical variations may require alternative treatments. Diagnostic ultrasound determines candidacy.

Both procedures achieve similar long-term closure rates. VenaSeal’s primary advantage is eliminating tumescent anesthesia, resulting in less discomfort, faster recovery, and no compression stocking requirement. Laser ablation may be preferred for specific anatomical situations.

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Danielle Killingsworth, NCMA, Aesthetics Coordinator at Colorado Skin & Vein in Denver

Danielle Killingsworth

NCMA, Aesthetics Coordinator

Danielle is a Colorado native who brings more than 22 years of experience in the medical field. Throughout her career she has developed a diverse clinical background across infectious disease, general surgery, and pain management — giving her a well-rounded understanding of patient care and of what it takes to create a safe, comfortable, and personalized experience.

As Aesthetics Coordinator at Colorado Skin & Vein, Danielle combines that clinical knowledge with a genuine passion for aesthetics. She is dedicated to helping patients feel confident, informed, and supported throughout their aesthetic journey, from the initial consultation through treatment and follow-up care.

She believes one of the most rewarding parts of her career is building meaningful relationships with patients and helping them look and feel their very best.

Outside of work, Danielle enjoys spending time with her family, including her four boys, getting lost in a good book, and working in her garden. Fun fact: she is a dedicated Dallas Cowboys fan.

Nikki Moyta, Operations Director at Colorado Skin & Vein in Denver

Nikki Moyta

Operations Director

For over 26 years, Nikki has dedicated her career to the dermatology and aesthetics industry, building her experience from the ground up — starting in a patient scheduling call center, moving to the front desk, and rising to executive leadership overseeing multiple providers and locations.

Originally from Pittsburgh, she moved to Orlando before starting 10th grade and later attended Seminole State College of Florida. Her career in dermatology began in 2002, scheduling appointments for a multi-location practice. She grew quickly within the organization, moving into front-desk and checkout roles before being promoted to Office Manager in 2008. In 2012, her leadership and operational expertise led the CEO to seek her out for an expanded role overseeing multiple providers and locations — a position she held through 2022.

Outside of her professional career, Nikki is passionate about giving back to the community:

  • Community outreach
  • Voted “Cheerleader of the Practice”
  • 1st Place Winner — Miles for Melanoma

With a career built on leadership, dedication, and a genuine passion for patients and the aesthetics industry, she is excited to bring her experience and enthusiasm to the Colorado community. When she is not in the office, you can find Nikki with her Siberian husky, Compass, somewhere on top of a mountain.

Betina Lacson, RVT at Colorado Skin & Vein in Denver

Betina Lacson

RVT

Betina graduated from the Cardiovascular Technology Program at Grossmont College in California in 2020, and brings more than six years of experience in the duplex world of venous insufficiency. Much of her career has centered on superficial vein mapping and assisting in surgery while providing attentive patient care.

At Colorado Skin & Vein, she assists with venous ablation procedures as well as ultrasound-guided sclerotherapy. She is committed to quality care at every stage — from the initial consultation, through surgery, to post-operative appointments — making sure each patient feels fully supported.

In her free time, Betina loves Kizomba dancing with her Afro-Latin dance community, and can often be found at electronic dance music shows in different cities. If you are feeling generous, she will happily accept a karaoke room or an iced Thai milk tea.

Brooke Owens, PA-C, MPAS at Colorado Skin & Vein in Denver

Brooke Owens

PA-C, MPAS

Brooke Owens, PA-C, MPAS is a compassionate Physician Assistant who brings a strong clinical foundation, exceptional attention to detail, and a patient-centered approach to Colorado Skin & Vein.

Prior to joining the practice, Brooke spent several years in pediatric primary care, caring for patients with a wide range of acute and chronic conditions. She became known for her thorough evaluations, thoughtful clinical decision-making, and ability to build lasting relationships with patients and their families. That experience strengthened her diagnostic expertise while reinforcing the importance of listening carefully, educating patients, and creating individualized treatment plans.

Drawn to the unique blend of medicine, procedures, and patient transformation, Brooke was excited to move into vascular medicine and aesthetic care. She is passionate about helping patients improve not only their health but also their confidence — whether they are seeking treatment for vein disease, skin concerns, or cosmetic enhancements. By combining broad medical experience with advanced specialty training and a meticulous eye for detail, she delivers safe, effective, and personalized care.

Brooke believes the best outcomes begin with trust. She values taking the time to understand each patient’s goals, answer questions, and ensure they feel informed and comfortable throughout their care.

Angel Croce, Staff Manager at Colorado Skin & Vein in Denver

Angel Croce

Staff Manager

Angel has been in healthcare for more than 20 years. Her journey began in 2004, after her father suddenly passed away from a stroke. Losing him was a life-changing experience, and it inspired her to choose a career where she could help others and give patients and their families the care, compassion, and support they need during difficult times.

Throughout her career she has worked across cardiology, neurology, family practice, and urgent care — each experience helping her grow both personally and professionally. She now works in vascular care and aesthetics, where she enjoys building relationships with her patients, helping them understand their care, and making sure they feel comfortable and supported throughout their journey.

Outside of work, Angel is a proud mom of two. Family is incredibly important to her, and in her spare time she loves being outdoors with her husband and their two dogs — hunting, fishing, and enjoying Colorado.

For Angel, healthcare is more than a career — it is personal. What started as a way to honor her father’s memory has become more than two decades of caring for others, and she is grateful to keep doing something that means so much to her every day.